Which of the following is a common route of contamination in sterile compounding?

Airborne particles are a well-documented route of contamination in sterile compounding environments. When preparing sterile medications, maintaining an aseptic environment is crucial to prevent microbial contamination. Airborne particles can carry bacteria and other pathogens that can settle on surfaces or into the compounding area, posing a significant risk to sterility.

The presence of airborne contamination can be exacerbated in environments where cleanroom protocols are not strictly followed or where there are disturbances that allow particles to infiltrate. This is why sterile compounding facilities typically employ various measures, such as high-efficiency particulate air (HEPA) filters, controlled airflow systems, and regular monitoring of air quality, to minimize the risk posed by airborne particles.

Understanding the potential sources of contamination helps in developing effective strategies to maintain sterility. It's not merely about eliminating contamination sources but also about creating an environment where these sources are continuously controlled and monitored.