When should a compounded sterile preparation (CSP) be discarded?

A compounded sterile preparation (CSP) should be discarded when contamination is suspected or if established guidelines are not followed. This ensures safety and efficacy for patients receiving these preparations. Contamination can lead to infections or adverse reactions, making it critical to adhere to sterility and quality standards throughout the compounding process.

If guidelines are not followed—such as improper aseptic technique, inadequate cleaning, or incorrect storage conditions—the integrity of the CSP is compromised. Discarding the preparation in these situations prevents the administration of potentially unsafe products to patients.

In contrast, while the other choices involve conditions that might necessitate discarding a CSP, they do not encompass the primary aspect of ensuring sterility and adherence to protocols that directly correlate with patient safety.