When ACDs are used regularly, how often should they be calibrated?

Calibrating Automatic Compounding Devices (ACDs) daily is essential to ensure their accuracy and reliability in sterile compounding practices. Frequent calibration is necessary because any deviations in measurements can lead to incorrect dosages, potentially posing risks to patient safety.

Regular calibration helps to identify any variations or inaccuracies in the device’s performance, which can occur due to factors such as wear and tear, environmental conditions, or the inherent variability of the components. By performing daily calibration, pharmacists reinforce the integrity of the compounding process, maintaining compliance with USP 797 standards. This practice not only supports the production of safe and effective compounded sterile preparations but also fosters a culture of diligence and quality assurance within the compounding environment.