What is the correct duration for running LAFW blowers before compounding?

The correct duration for running the laminar airflow workbench (LAFW) blowers before compounding is 30 minutes. This period ensures that the airflow within the work area has stabilized, allowing the sterile environment to be effectively maintained. Running the blowers for this amount of time helps to clear any possible contaminants from the area and ensures that the airflow is undisturbed, providing a consistent and controlled environment for sterile compounding.

In a sterile compounding setting, it's essential that personnel adhere to guidelines that optimize sterility and minimize the risk of contamination. It is well established in sterile compounding protocols that proper startup time is crucial. By allowing the LAFW to run for 30 minutes, the air harmonizes, ensuring proper ventilation patterns and sufficient air velocity is achieved, creating an aseptic area for the preparation of sterile medications. This practice is a fundamental part of maintaining compliance with USP 797 guidelines.