How often should air sampling and surface sampling be conducted in sterile compounding areas?

The correct answer indicates that air sampling and surface sampling should be conducted at least every six months in sterile compounding areas. This frequency is critical for ensuring compliance with the standards set forth by USP 797, which aims to minimize the risk of contamination in sterile compounding environments. Regular sampling helps identify any potential microbial contamination in the air and on surfaces, allowing for timely corrective actions to be implemented.

By adhering to this six-month interval, facilities can maintain a consistent monitoring schedule that supports the integrity of the sterile compounding process. This is essential for protecting patient safety and ensuring that compounded sterile preparations meet the necessary quality standards. Regular sampling also provides a historical data set that can be analyzed for trends over time, enabling proactive adjustments to procedures and practices within the facility.