Can a Compounding Sterile Preparation be reused after leaving the pharmacy?

In the context of USP 797 guidelines, a Compounding Sterile Preparation (CSP) should not be reused after leaving the pharmacy. This is primarily due to the risk of contamination and compromised sterility that can occur once the CSP has been dispensed. Sterility is a critical factor in patient safety, and once a CSP is labeled and leaves the pharmacy, it can no longer be guaranteed to meet the required standards for sterility, as it may be exposed to varying environmental factors and handling that can introduce microorganisms.

Additionally, reusing a CSP raises significant concerns regarding the stability and efficacy of the preparation. Products are not typically validated for reuse after being dispensed, and re-dispensing without proper oversight can lead to serious implications for patient safety. Therefore, once a CSP has been dispensed, it should not be administered or re-used, reinforcing the necessity of proper preparation and handling protocols within the pharmacy setting.